---
title: "GIP"
description: "GIP is an incretin hormone targeted alongside GLP-1 by tirzepatide for diabetes and obesity."
canonical: "https://www.kesho.health/glossary/gip"
markdown_url: "https://www.kesho.health/md/glossary/gip"
language: "en-IN"
---

# GIP

**Canonical HTML:** https://www.kesho.health/glossary/gip  
**Markdown:** https://www.kesho.health/md/glossary/gip

## Definition

GIP (glucose-dependent insulinotropic polypeptide) is a gut incretin that stimulates insulin release and affects fat metabolism.

## Extended

Tirzepatide is a dual GIP/GLP-1 receptor agonist. GIP activation may contribute to greater weight and glycaemic effects compared with GLP-1-only agents in trials. In India, these concepts appear in RSSDI and ICMR guidance for type 2 diabetes and obesity care—always confirm details with your prescribing physician.

## Learn more

[Full guide](https://www.kesho.health/blog/semaglutide-vs-tirzepatide) · [MD](https://www.kesho.health/md/blog/semaglutide-vs-tirzepatide)

## Related terms

- [incretin](https://www.kesho.health/glossary/incretin)
- [tirzepatide](https://www.kesho.health/glossary/tirzepatide)
- [glp-1](https://www.kesho.health/glossary/glp-1)