---
title: "Incretin"
description: "Incretins are gut hormones including GLP-1 and GIP that stimulate insulin release—targeted by GLP-1 receptor agonist medicines."
canonical: "https://www.kesho.health/glossary/incretin"
markdown_url: "https://www.kesho.health/md/glossary/incretin"
language: "en-IN"
---

# Incretin

**Canonical HTML:** https://www.kesho.health/glossary/incretin  
**Markdown:** https://www.kesho.health/md/glossary/incretin

## Definition

Incretins are intestinal hormones released after meals that amplify insulin secretion in a glucose-dependent manner.

## Extended

GLP-1 and GIP are the main incretins. GLP-1 receptor agonists mimic GLP-1; tirzepatide activates both GIP and GLP-1. DPP-4 inhibitors prolong natural incretin action by a different mechanism. In India, these concepts appear in RSSDI and ICMR guidance for type 2 diabetes and obesity care—always confirm details with your prescribing physician.

## Learn more

[Full guide](https://www.kesho.health/blog/glp-1-explained-india) · [MD](https://www.kesho.health/md/blog/glp-1-explained-india)

## Related terms

- [glp-1](https://www.kesho.health/glossary/glp-1)
- [gip](https://www.kesho.health/glossary/gip)
- [glp-1-receptor-agonist](https://www.kesho.health/glossary/glp-1-receptor-agonist)