---
title: "MEN2"
description: "MEN2 (Multiple Endocrine Neoplasia type 2) is a contraindication to GLP-1 receptor agonist therapy."
canonical: "https://www.kesho.health/glossary/men2"
markdown_url: "https://www.kesho.health/md/glossary/men2"
language: "en-IN"
---

# MEN2

**Canonical HTML:** https://www.kesho.health/glossary/men2  
**Markdown:** https://www.kesho.health/md/glossary/men2

## Definition

MEN2 is a rare inherited syndrome causing medullary thyroid cancer, phaeochromocytoma, and hyperparathyroidism due to RET gene mutations.

## Extended

Family history of MEN2 or medullary thyroid carcinoma contraindicates GLP-1 medicines. Genetic counselling may be appropriate when history is uncertain. In India, these concepts appear in RSSDI and ICMR guidance for type 2 diabetes and obesity care—always confirm details with your prescribing physician.

## Learn more

[Full guide](https://www.kesho.health/blog/glp-1-and-thyroid-what-to-know) · [MD](https://www.kesho.health/md/blog/glp-1-and-thyroid-what-to-know)

## Related terms

- [medullary-thyroid-carcinoma](https://www.kesho.health/glossary/medullary-thyroid-carcinoma)